Which of the following diseases is NOT associated with Streptococcus Pyogenes according to the mnemonic "GET NIPPLES"?

• A. Endocarditis
• B. Necrotizing fascitis
• C. Pneumonia
• D. Erysipelas

Answer: (C)

The mnemonic "GET NIPPLES" is used to remember the diseases associated with Streptococcus pyogenes, which include conditions such as Group A Streptococcal infections. Each letter in the mnemonic corresponds to a specific disease or condition.

In this context, "Pneumonia" does not fall under the diseases typically associated with Streptococcus pyogenes. While Streptococcus pneumoniae is a notable bacterial pathogen that indeed causes pneumonia, Streptococcus pyogenes (Group A Streptococcus) is better known for causing conditions such as pharyngitis (strep throat), rheumatic fever, scarlet fever, and skin infections like erysipelas and necrotizing fasciitis.

The absence of pneumonia from Streptococcus pyogenes’ list of associated diseases reinforces the distinction between these two streptococcal species, emphasizing the need to be aware of their different clinical profiles. Thus, pneumonia is correctly identified as the option that does not belong in the context of diseases linked to Streptococcus pyogenes.