What mnemonic helps to recall the neurotransmitters affected in depression?

• A. LIBIDO, NOREPINEPHRINE, DOPAMINE
• B. STRESS, NOREPINEPHRINE, DOPAMINE
• C. SEROTONIN, NOREPINEPHRINE, DOPAMINE
• D. STIMULANT, NOREPINEPHRINE, DOPAMINE

Answer: (C)

The correct answer highlights the neurotransmitters most commonly associated with depression, namely serotonin, norepinephrine, and dopamine. This collection of neurotransmitters plays a crucial role in mood regulation, and deficiencies in these chemicals are often linked to the pathophysiology of depressive disorders.

Serotonin is particularly vital as it helps regulate mood, anxiety, and overall emotional well-being. Lower levels of serotonin are frequently observed in individuals with depression, and many antidepressant medications aim to increase serotonin levels in the brain.

Norepinephrine contributes to arousal and alertness and also impacts energy levels and mood. Its imbalance can lead to depressive symptoms, and drugs that target norepinephrine pathways may help alleviate these symptoms in patients.

Dopamine is associated with the brain's reward system and motivation. A decline in dopamine has been connected to anhedonia (the inability to feel pleasure), which is a hallmark symptom of depression.

Together, these neurotransmitters form a triad that is essential for understanding the neurochemical basis of depression, making this mnemonic particularly effective for healthcare professionals studying mental health and its treatments.